EI Associates was retained by Hemispherx Biopharma Inc. to provide detailed design, procurement and construction management services for their new Alferon N Injection Process Suite “Scale-Up” project. EI assisted Hemispherx with the commercialization of one of their process units which involved the expansion of the existing New Brunswick, NJ facility to accommodate new process equipment and systems.

The new process suites include larger batch equipment, new bioreactors as well as the use of continuous centrifugation. Our design has resulted in reduced labor cost, the alleviation of bioburden concerns, required a smaller manufacturing footprint within the facility and provided for a dramatically more cost effective production process. EI designed and built all process related improvements as well as architectural, structural, HVAC and electrical system upgrades to support the new process suite.